| Genome 562 | Population Genetics |
| Spring, 2007 | J. Felsenstein |
| Date | Topic | Reading | ||
| March 26 | Introduction; Hardy-Weinberg proportions | I.1-I.3 | ||
| 28 | Multiple alleles, difft. sexes | I.4, I.6 | ||
| 30 | Sex-linkage | I.7 | ||
| 2 | Linkage and linkage disequilibrium | I.8 | ||
| 4 | Natural Selection | II.1-II.2 | ||
| 6 | " " | II.4, II.5 | ||
| 9 | Polymorphisms and fitness | II.6-II.8 | ||
| 11 | " " " | II.9-II.11 | ||
| 13 | Kin, group and species selection | II.12 | ||
| 16 | Mutation | III.1-III.3 | ||
| 18 | Maintenance of deleterious mutants | III.4-III.6 | ||
| 20 | Migration, Clines | IV.1-IV.11 | ||
| 23 | " " | " " | ||
| 25 | Inbreeding in pedigrees | V.1-V.5 | ||
| 27 | Regular systems of mating | V.10-V.12, V.14 | ||
| 30 | Inbreeding depression | V.13 | ||
| May 2 | Genetic drift | VI.1-VI.4 | ||
| 4 | Effective population size | VI.5-VI.7 | ||
| 7 | Neutral mutation theory | VII.1-VII.2 | ||
| 9 | Trees of genes | X.4-X.6 | ||
| 11 | Trees of genes II -- the sequel | X.8 | ||
| 14 | Molecular evolution | VII.7, VII.8 | ||
| 16 | Drift and other forces | VII.4,VII.5,VII.8,VII.9 | ||
| 18 | Drift and other forces | " " " " | ||
| 21 | Genetics of quantitative characters | IX.1-IX.5 | ||
| 23 | Components of variance | IX.6-IX.9 | ||
| 25 | Selection response | " " | ||
| 28 | HOLIDAY
(Memorial Day; last day of Folk Life Festival) | |||
| 30 | Finding QTLs | (none) | ||
| June 1 | Finding QTLs | (none) |
Exams: none.
Text: Theoretical Evolutionary Genetics, by Joe Felsenstein, publication to be arranged, hopefully about $25
The text is also available as a PDF that can be downloaded:
from this link
Course web page: http://evolution.gs.washington.edu/gs562/2007/