Week 10: Consensus trees, tree distances
Where is the lecture room?
It is in Fisheries Building room 108. The building is
here
(along Boat Street opposite the University Police offices)
The course text and how to get it
The course text is my book,
Inferring Phylogenies, published by Sinauer Associates.
The University Book Store (South Campus Center branch) has copies. It can
also be
ordered from Sinauer Associates or from Amazon. The first printing of the
book has many typos. A web page listing the typos is available. Many of these were corrected in
the second printing, and more in the third printing. If there is a box on the
back cover with reviews of the book, that is the second or third edition.
Some data sets you can download and use
Almost all the data sets used in the book can be downloaded from its
data sets web site.
These additional data sets are so that we can discuss common examples when
people try
out various programs. They are in PHYLIP formats, but these can often be
read by other programs such as PAUP and MacClade. These data sets can be
downloaded by clicking on the appropriate words. If clicking on
them happens to display the file rather than open a window that asks you
where to put the file, you may be able to get your browser to save it by
using a "Save As" function (on most browsers that's in the Files menu).
- A 15-species, 40-character discrete-characters (0/1) data set
of fossil elephants by Pascal Tassy and Pierre Darlu. From a paper in
Geobios 19: 587-600 1986. Click here to download.
- A 16-species, 1992-site DNA data set from the paper by Clint
Turbeville and others:
Turbeville. J. McC., Schulz, J .R. and R. A. Raff.
1994. Deuterostome phylogeny and the sister group of the chordates: evidence from
molecules and morphology. Molecular Biology and Evolution 11: 648-655.
Alignment is by them. These are chordates, protochordates, echinoderms,
thisachordates, and thatachordates. Heavy-duty industrial-strength data.
These sequences are in interleaved format.
Click here to download.
- A 76-species protein sequence data set for Transcription Elongation
Factor Alpha (EFTU-alpha), alignment by the Protein Information Resource
of the National Biomedical Research Foundation.
Click here to download.
Some species are represented more than once, and some by fragments.
I will be putting up some more datasets.
What are some other related courses?
- Biology 354 Foundations in Evolution and Systematics
- The main evolution course at the University, taught twice yearly (Winter and Spring). Text is the 3rd edition of
Freeman and Herron's "Evolutionary Mechanisms".
This year course was taught by Toby Bradshaw in the
Winter quarter, and is being taught by Peter Ward and Ray Huey in the
Spring Quarter.
- Genome 453 (Evolutionary Genetics)
- This is an
undergraduate-level course on evolution and genetics. Given every
Autumn, it overlaps somewhat with Biology 354 but
covers the genetic aspects of evolution with less emphasis on
ecology and paleontology than the first, less emphasis on molecular
evolution than the second.
It should be understood that this is basically an undergraduate course.
- Genome 562 (Population Genetics)
- Now given every other year, this is the graduate theoretical
evolutionary genetics course that I give. Lots of equations, though
mostly at a low mathematical level. No pictures of cute furry animals.
Next time it's given will be Spring, 2009. Text: my own extensive lecture
notes, downloaded
as PDF's for free or sold inexpensively (no royalty is paid to me).
What are some Internet resources on evolutionary biology?
There are many:
Electronic journals
There is of course, the professional literature in evolutionary
biology. Some of these journals (links given below) are available in
electronic versions for UW people. Here are some:
Newsgroups
Some brief descriptions of some of the major ones covering evolution. These
groups have many participants who are novices to evolutionary biology.
I have provided links to the groups through Google, but UW students
can read them using UW's newsreading facilities too. Unfortunately,
Usenet newsgroups are dying out, with people shifting to Yahoo groups and
blogs. These have not yet achieved the level of general discussion that
the Usenet groups have, so the number of Internet resources for serious
discussion of evolutionary biology has actually decreased.
-
sci.bio.systematics
- Discussion of systematics, including phylogeny and classification.
Most postings are serious discussions by researchers. Some percentage
of them are semantic issues or legalistic discussions of taxon names.
There has sometimes been an endless thread about cladistic versus evolutionary-systematic
approaches to classification. Lately there is almost no traffic.
-
bionet.molbio.evolution
- Discussion among researchers about molecular evolution. Low
volume, high quality. Co-moderated by Jerry Learn of our Micro Department.
Very inactive lately.
-
sci.bio.paleontology
- Tends to be filled with postings by fossil enthusiasts and
tends to be dinosaur-centered. Some creation/evolution debating too.
-
sci.bio.evolution
- Moderated by Josh Hayes, formerly of our own Center for Quantitative Sciences, who
should get some sort of award for putting up with a lot of nonsense.
I think it was intended as a forum for discussion among researchers, but has
tended to be filled with postings by others about whether humans are still evolving
(answer: yes, but it's extremely slow compared to cultural change) and
whether laughter is selectively advantageous. There is often an endless
controversy of everybody against a couple of people who think they've proven
that Hamilton's formula for kin selection is wrong (they haven't). Not intended for
evolution/creation debates: Josh screens these out.
-
talk.origins
- The arena for endless debate between creationists and others, with
frequent digressions into theology. Extremely high noise to signal ratio.
When a decisive point is made, the opponent changes the subject or just
refuses to respond.
Web Pages
- The amazing Tree of Life , a phylogeny of all life, in the
making. A professional data base system of systematics, in effect.
- TreeBASE, a database of evolutionary trees (phylogenies)
from the scientific literature. Weighted towards flowering plants, and
badly suffers being only sporadically updated.
- My own
PHYLIP free package of computer programs for inferring phylogenies.
Includes some web pages on all possible phylogeny programs and how to get
them.
- The
University of California Museum of Paleontology
pages, which include a substantial evolution and phylogeny section. This is
a sort of "virtual museum".
- Want some DNA or protein sequences? How about getting them from the
international database? Try the Web pages of the databases at the
NCBI, the National Center for Biotechnology Information of the National
Library of Medicine, in Bethesda, Maryland. Not for the faint-hearted.
- The
talk.origins Evolution FAQs (Frequently Asked Questions).
- The Harvard Biopages evolution page, with lots of links to other
evolution resources.
This page maintained fitfully by Joe Felsenstein